Centres Of Excellences

Molecular Oncology

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Molecular Oncology has now become an essential part of cancer diagnosis and treatment. Identification of genetic changes in hereditary cancer syndromes such as neurofibromatosis, Lynch syndrome, hereditary breast and ovarian cancer syndrome are now essential part of routine diagnosis tests in cancer care worldwide. Also, specific molecular diagnostics tests are required now for selecting chemotherapeutic regimen in certain cancers such as adenocarcinomas of lung for better survival rate and quality of life. The molecular oncology diagnostics requires a streamlined work-flow starting from good quality histopathological examination, leading on to tailor-made and affordable molecular biology assays, analysis that ultimately translatable into clinically meaningful interpretations. Experts in oncology, pathology and molecular biology departments in Amrita Institute of Medical Sciences have joined hands to make this possible in a seamless way to proliferate an efficient and advanced genetic and genomic level variance detection in cancer diagnostics. Please see the following list of tests we have currently introduced in Amrita Molecular Oncology Laboratory.

Facilities

  1. NABL accredited molecular biology laboratory
  2. Onco-pathologists directed tissue triaging and sampling
  3. High quality molecular biology grade reagents and standards
  4. State-of-the art equipments such as
    1. Thermo ABI 7500 Fast® Real-time PCR
    2. Qiagen Roto-Gene® Real-time PCR
    3. Thermo Veriti Thermal Cycler
  5. Separate stations for DNA/RNA biosafety cabinets
  6. Separate labs for DNA extraction, pre-PCR mixture, post PCR processing etc
  7. Sequencing and fragment analysis done in different facilities
  8. Custom made assays with proper validation and controls
  9. Double validation of mutational variants using two different techniques ultimately confirmed by DNA sequencing or fragment analysis
  10. Advanced tests with affordable price
  11. Analysis using professional software and publicly available databases
  12. Handled by experts who are both clinicians and molecular biologists so that analysis, troubleshooting and clinical interpretation is all streamlined
  13. Pre-test counseling: Introduction to genetic test and pre-test counseling done routinely by clinical onco-geneticist
  14. Post-test interpretation of result, analysis details and implications are explained routinely

 

Services Offered

Research Activities

Many new research studies have been initiated with the co-ordination of all the clinical, and non-clinical departments.  For e.g. Amrita Phakomatoses Clinic. A specialized clinic to screen patients who have been suspected to have hereditary phakomatoses syndromes causing multiple tumors in the brain and spinal cord and other nervous system related regions of the body. The disorders include neurofibromatosis type 1-, type 2, von Hippel Lindau syndrome, Gorlin syndrome etc. The clinic is a coordinated effort of Neurosurgery, Neurology, Urology, GI surgery, Endocrinology, Ophthalmology, Paediatric Genetics and Molecular Diagnostics Division of Medical Oncology.

 

Contact Us

Medical Oncology, Molecular Diagnostics Division;
Amrita Institute of Medical Sciences
AIMS Ponekkara P.O. Kochi, India 682041
Phone - Office: (+91) 484 285 2250; Mobile: (+91) 703 402 8814
Email: prasanthas@aims.amrita.edu